Role of enhancement features of cerebral venous sinus in the diagnosis of cerebral venous sinus thrombosis: a MRI study
10.3760/cma.j.issn.1006-7876.2015.12.009
- VernacularTitle:颅内静脉窦血栓形成患者静脉窦MRI强化特征研究
- Author:
Qian LI
;
Chenglin TIAN
;
Yawen YANG
;
Bin LYU
;
Chuanqiang PU
- Publication Type:Journal Article
- Keywords:
Cerebral venous sinus thrombosis;
Magnetic resonance imaging;
Contrast enhancement
- From:
Chinese Journal of Neurology
2015;48(12):1079-1083
- CountryChina
- Language:Chinese
-
Abstract:
Objective To describe the changes of thrombosed venous sinus on MRI after administration of contrast material and evaluate the sensitivity and specificity of thread-like enhancement around sinus to diagnose thrombosis in the corresponding sinus.Methods Patients with cerebral venous sinus thrombosis (CVST) admitted to our department from January 2005 to December 2014 and undergone a MRI scan with administration of contrast material were included in this study.The enhancement features of venous sinus were studied in the plane parallel to the interested sinus.The features of enhancement were classified as peripheral thread-like enhancement, partial enhancement and complete enhancement.The proportion of these three type of enhancement in thrombosed sinuses and normal sinuses were described and compared.The sensitivity and specificity of peripheral thread-like enhancement to diagnose thrombosis in corresponding sinus were calculated.The proportion of each type of enhancement was also described and compared in acute (≤ 7 d), subacute (8-30 d) and chronic (≥ 31 d) stage after onset of symptoms.Results Peripheral thread-like enhancement, partial enhancement and complete enhancement were all found in both thrombosed and normal sinuses.There was a significant difference of enhancement features between normal and thrombosed sinus in superior sagittal sinus (100％ (30/30) vs 60％ (27/45), x2 =13.789, P =0.001), left trans verse sinus, and right sigrnoid sinus.The sensitivity and specificity of peripheral thread-like enhancement to diagnose thrombosis in the corresponding sinus were 10.5％-44.4％ and 53.3％-76.7％ respectively.There was no significant difference of contrast features at different stage after onset.Conclusion The value of peripheral thread-like enhancement to diagnose CVST is limited because of low sensitivity and specificity.
