Argatroban in treatment of patients with transient ischemic attack
10.3760/cma.j.issn.1671-7368.2015.12.014
- VernacularTitle:阿加曲班治疗短暂性脑缺血发作的临床观察
- Author:
Xiaoze LI
;
Qing LIU
;
Bingqing WANG
;
Weirong LI
- Publication Type:Journal Article
- Keywords:
Ischemic attack,transient;
Anticoagulants
- From:
Chinese Journal of General Practitioners
2015;14(12):951-953
- CountryChina
- Language:Chinese
-
Abstract:
Eighty-three patients with transient ischemic attack (TIA) were randomly divided into study group (n =42) and control group (n =41) from July,2011 to Mar,2015.Patients in both groups were given aspirin 100 mg/d ; in addition,patients in study group received intravenous infusion of argatroban 10 mg,q12h,for 7 days and those in control group received subcutaneous injection of low molecular weight heparin (LMWH) 2 050 AXa IU,b.i.d for 7 days.The cases with cure,significantly effectiveness and effectiveness in study group and control group were 10,14,16 and 6,12 16,respectively.Compared with the control group,argatroban shows superiority in treatment of TIA with higher safety and lower side effect.