Chronic Hydroxyurea-induced Dermatomyositis-like Eruption Showing Epidermal Dysmaturation.
10.5021/ad.2002.14.1.28
- Author:
Jae Hong PARK
;
Chang Duk KIM
;
Young Wook RYOO
;
Byung Chun KIM
;
Kyu Suk LEE
- Publication Type:Case Report
- Keywords:
Hydroxyurea;
Epidermal dysmaturation;
Dermatomyositis
- MeSH:
Dermatomyositis;
Epidermis;
Hand;
Humans;
Hydroxyurea;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
- From:Annals of Dermatology
2002;14(1):28-30
- CountryRepublic of Korea
- Language:English
-
Abstract:
Hydroxyurea is an effective treatment for a variety of myeloproliferative disodrers. A distinct cutaneous reaction to long-term administration of hydroxyurea has been characterized and designated hydroxyurea dermopathy. Epidermal dysmaturation refers to histologic changes that may be observed in the epidermis after any significant cytoreductive therapy. We report a patient with hydroxyurea-induced dermatomyositis-like eruption showing epidermal dysmaturation who developed an erythematous scaly patches on the dorsal aspects of the hands while on long-term administration of hydroxyurea for chronic myelogenous leukemia.
