Research progress of the relationship between c-Abl and solid tumors
10.3760/cma.j.issn.1006-9801.2016.03.019
- VernacularTitle:c-Abl与实体瘤关系研究进展
- Author:
Wei LI
;
Xiujun SONG
- Publication Type:Journal Article
- Keywords:
c-Abl;
Tyrosine kinase;
Solid tumors
- From:
Cancer Research and Clinic
2016;28(3):213-216
- CountryChina
- Language:Chinese
-
Abstract:
Non-receptor tyrosine kinase c-Abl has been implicated in the regulation of the cell cycle,adhesion, apoptosis and DNA damage responses.Its excessive activation is related with the development of chronic myeloid leukemia, and the relationship between c-Abl and leukemia is in depth and detailed research.In contrast to leukemia, the research between c-Abl and solid tumors is just at the early stage.This paper briefly reviews research progress of the c-Abl in solid tumors.
