Research progress of matrix metalloproteinases in endometrial carcinoma metastasis
10.3760/cma.j.issn.1006-9801.2016.03.018
- VernacularTitle:基质金属蛋白酶在子宫内膜癌转移中的研究进展
- Author:
Huijuan GUAN
;
Yuqi ZHAI
;
Xin MENG
- Publication Type:Journal Article
- Keywords:
Endometrial cancer;
Matrix metalloproteinases;
Metastasis
- From:
Cancer Research and Clinic
2016;28(3):210-212
- CountryChina
- Language:Chinese
-
Abstract:
Tumor cell metastasis is a process of extracellular matrix hydrolyzed by protease, where tumor cells traverse the defect in the extracellular matrix into the lymphatic system and the capillaries to form new metastasis hematogenously.Matrix metalloproteinases (MMPs) are a kind of enzymes closely related to the metastasis.MMP, especially the relationship between MMP-9 and endometrial cancer metastasis in this paper will be summarized to get a better understanding about it.