Advances in applying DNA methylation as the biomarkers of hepatocellular carcinoma
10.3760/cma.j.issn.1009-9158.2016.02.003
- VernacularTitle:肝癌中DNA甲基化标志物的研究进展
- Author:
Yuguang LI
;
Fenyong SUN
- Publication Type:Journal Article
- Keywords:
Carcinoma,Hepatocellular;
DNA Methylation;
Early Diagnosis;
Prognosis;
Tumor Markers,Biological
- From:
Chinese Journal of Laboratory Medicine
2016;39(2):79-81
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma (HCC) is a malignant tumor with high morbidity and high mortality.Early diagnosis is the key for HCC treatment.DNA methylation is one of the important mechanisms of epigenetic genetics.To investigate the mechanism of DNA methylation can provide a theoretical basis for the diagnosis of HCC,and the methylation level of the specific genes can also be used as the biomarkers of HCC for the early diagnosis and prognosis evaluation.
