The value and controversy of thyroid peroxidase antibody in the diagnosis and treatment of autoimmune thyroid disease
10.3760/cma.j.issn.1009-9158.2015.12.023
- VernacularTitle:甲状腺过氧化物酶抗体在自身免疫性甲状腺疾病诊治中的价值及存在问题
- Author:
Hui FAN
;
Guang WANG
- Publication Type:Journal Article
- Keywords:
Thyroid Diseases;
Thyroiditis,autoimmune;
Iodide peroxidase;
Autoantibody
- From:
Chinese Journal of Laboratory Medicine
2015;38(12):884-887
- CountryChina
- Language:Chinese
-
Abstract:
Thyroid peroxidase antibody (TPOAb) play an important role in the diagnosis of autoimmune thyroid disease.Chemiluminescence immunoassay (CLIA) is a new method been strongly recommended in recent years.The definition of positive value of TPOAb is inconsistent.The definition of TPOAb positive value is important for exploring the development of autoimmune thyroid disease.TPOAb is significantly increased in Hashimoto's disease and the titer is associated with the degree of infiltration and destruction of thyroid follicular.It is essential to monitor TPOAb in postpartum thyroiditis and early pregnancy.The positive of TPOAb is closely related to the adverse pregnancy outcomes caused by various risk factors.Graves disease combined with Hashimoto's must to be considered.
