A novel and rapid detection method for carbapenemases: the Carba NP test
10.3760/cma.j.issn.1009-9158.2015.12.022
- VernacularTitle:新型碳青霉烯酶快速检测方法:Carba NP试验
- Author:
Xin FAN
;
Yingchun XU
;
Yupei ZHAO
- Publication Type:Journal Article
- Keywords:
Bacterial proteins;
beta-Lactamases;
Anti-bacterial agents;
Enterobacteriaceae;
Microbial sensitivity tests
- From:
Chinese Journal of Laboratory Medicine
2015;38(12):881-883
- CountryChina
- Language:Chinese
-
Abstract:
The worldwide spread of carbapenem-resistant Gram-negative bacteria has become a major threat to public health.Being different from other resistance mechanism,most of the carbapenemase-encoding genes are located on mobile genetic elements.It speeds up the emerging of carbapenem-resistant strains and impose severe challenges to clinical treatment and infection control.The Carba NP test is a rapid,reliable and economical method for detection of carbapenemases.In particular,the method has superior specificity to Ambler classes A and B carbapenemases.Application of this rapid carbapenemase-detection assay will benefit clinical practice,antibiotic stewardship and prevention for the development of nosocomial resistant bacteria.
