The diagnostic and predictive value of long noncoding RNAs in ischemic heart disease
10.3760/cma.j.issn.1009-9158.2015.12.021
- VernacularTitle:长链非编码RNA在缺血性心脏病中的诊断和预测价值
- Author:
Li ZHANG
;
Dewei WU
;
Haiyan QIAN
;
Mengyue YU
- Publication Type:Journal Article
- Keywords:
Myocardial ischemia;
RNA,long noncoding;
Forecasting
- From:
Chinese Journal of Laboratory Medicine
2015;38(12):877-880
- CountryChina
- Language:Chinese
-
Abstract:
Different types of noncoding RNAs (ncRNAs) are pervasively expressed in genomes of complex organisms.Current evidence suggests that long noncoding RNAs (lncRNAs) have significant roles at almost every stage of gene expression.It is an important regulatory factor involving in ischemic heart diseases,participating in the development of ischemic heart disease,expecting to predict early myocardial remodeling after myocardial infartion and heart failure,and attracting more and more attention.This review introduces the definition,classification,function and characteristics of lncRNA,and focuses on its diagnostic and predictive value in ischemic heart disease.
