Risk factors analysis for patients aged over 65 years undergoing combined heart valve surgery and coronary artery bypass grafting
10.3760/cma.j.issn.1001-4497.2016.03.007
- VernacularTitle:65岁以上患者心脏瓣膜手术同期行冠状动脉旁路移植术的危险因素分析
- Author:
Zhengbiao ZHA
;
Tao YANG
;
Hansong SUN
;
Yunhu SONG
;
Wei WANG
;
Jianping XU
;
Shengshou HU
- Publication Type:Journal Article
- Keywords:
Heart valve disease;
Coronary artery bypass grafting;
Aged;
Risk factors;
Hospital mortality
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2016;32(3):151-154
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors for in-hospital mortality in patients aged over 65 years undergoing heart valve surgery combined with coronary artery bypass grafting(CABG).Methods Between February 2002 and September 2014,540 patients aged over 65 years undergoing heart valve surgery combined with CABG in our institute were retrospectively studied.Univariate analyses and multivariate logistic regression analyses were performed to explore risk factors associated with in-hospital mortality.Results Overall in-hospital mortality was 4.26％.Univariate analysis depicted that chronic obstructive pulmonary disease (COPD) (P =0.001),last serum creatinine (P =0.043),unstable angina(P =0.046),Canadian Cardiovascular Society 111-ⅣV (P =0.005),number of diseased coronary vessels (P =0.043),cardiopulmonary bypass time-delayed (P =0.003),post-operative morbidity (P =0.000) had a significant impact on in-hospital mortality.Multivariate logistic regression analysis revealed that COPD (P =0.005,OR =5.598),CPB time-delayed (P ＜ 0.001,OR =1.011),re-exploration (P ＜0.001,OR =15.813),malignant arrhythmia (P =0.014,OR =4.900) were independent risk factors of in-hospital mortality.Conclusion The present research demonstrates that COPD,CPB time-delayed,re-exploration and malignant arrhythmia dramatically impacted the in-hospital mortality of patients aged over 65 years undergoing combined heart valve surgery and CABG.
