Low frequency, repetitive transcranial magnetic stimulation can alleviate non-fluent aphasia after stroke
10.3760/cma.j.issn.0254-1424.2016.03.003
- VernacularTitle:低频重复经颅磁刺激治疗脑卒中后非流畅性失语的疗效观察
- Author:
Ying SHEN
;
Zhifei YIN
;
Qiumin ZHOU
;
Fang CONG
;
Wenchao YI
;
Chunlei SHAN
- Publication Type:Journal Article
- Keywords:
Repetitive transcranial magnetic stimulation;
Stroke;
Non-fluent aphasia;
Western Aphasia Battery;
Communication Abilities in Daily Living
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2016;38(3):170-174
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of low frequency repetitive transcranial magnetic stimulation (rTMS) on non-fluent aphasia in patients after stroke.Methods Forty stroke patients displaying non-fluent aphasia were randomly assigned to an rTMS group and a control group using a random number table.Both groups were treated with conventional language therapy,while the rTMS group was additionally given 0.5 Hz rTMS over the Broca's homologues of the unaffected hemisphere 5 days a week for 3 weeks.The patients were stimulated at 90％ of the motor threshold (MT),with 16 second trains and intervals of 3 seconds 48 times (384 pulses) in a session.Before and after the 3 weeks of treatment,the Western Aphasia Battery (WAB) and the Communicative Abilities in Daily Living (CADL) test were conducted in both groups to evaluate their language function and communication ability.Results Only spontaneous speech improved significantly (P＜0.05) in the control group after 3 weeks of treatment.In the rTMS group,the spontaneous speech,auditory comprehension,repetition,naming and aphasia quotient (AQ) had all improved significantly (P＜0.05).Moreover,after the treatment,the average score of the auditory comprehension (153.90± 31.79),repetition (82.65± 15.14),naming(81.28±22.12) and AQ (63.66± 13.64) of the rTMS group were significantly higher than those of the control group (P＜0.05).Conclusion rTMS applied to the Broca's homologues of the unaffected hemisphere can significantly improve language function in those exhibiting non-fluent aphasia after stroke.
