Surgical strategy for gastric cancer patients complicating portal hypertension
10.3760/cma.j.issn.1007-631X.2016.02.001
- VernacularTitle:胃癌合并门静脉高压症的术式选择及疗效观察
- Author:
Yin ZHU
;
Zhengyun ZHANG
;
Zunqiang ZHOU
;
Jun YANG
;
Guangwen ZHOU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Hypertension,portal;
Gastrectomy
- From:
Chinese Journal of General Surgery
2016;31(2):89-92
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the outcome of surgical approaches in patients of gastric cancer with portal hypertension.Methods The clinical data of 80 patients with portal hypertension undergoing curative surgery for gastric cancer or simultaneous surgery for portal hypertension were retrospectively analyzed.Results The radical gastrectomy alone had no tremendous impact on postoperative liver function.But simultaneous surgery for portal hypertension affected patients' liver function dramatically (P =0.018).For those who underwent surgery for portal hypertension simultaneously,the incidence of complications in Child B patients was much higher than that in Child A patients (P =0.018).However,the incidence of complications did not differ between Child A and B patients who underwent radical gastrectomy alone.In addition,patients undergoing simultaneous surgery for portal hypertension had more severe complications than those who underwent radical gastrectomy only (P =0.042).Age > 50 (P =0.012),tumor stage (P =0.015),and simultaneous surgery for portal hypertension (P =0.007) were the independent risk factors for postoperative liver dysfunction.The survival time of patients undergoing simultaneous surgery for portal hypertension was significantly shorter than that of patients undergoing radical gastrectomy only (in Child A patients,P =0.009,in Child B patients,P =0.000).Conclusions Individualized surgical approaches for the treatment of gastric cancer with portal hypertension should be decided by preoperative liver function.Simultaneous management of portal hypertension was not recommended.