Clinical implications of plasma omentin levels in patients with polycystic ovary syndrome

VernacularTitle:多囊卵巢综合征患者血清网膜素水平变化及其意义
Author: Xinhong LU ; Haiyan YANG ; Zuojie LUO ; Yujuan FAN ; Yan MA
Publication Type:Journal Article
Keywords: Polycystic ovary syndrome; Omentin; Insulin resistance; Obesity
From: Chinese Journal of Endocrinology and Metabolism 2015;31(10):880-882
CountryChina
Language:Chinese
Abstract: This paper was to explore the relationship between plasma omentin and obesity and insulin resistance in patients of polycystic ovary syndrome(PCOS).The results showed that there were statistically significant differences in serum omentin levels among control group,PCOS-normal weight group,and PCOS-overweight group [(115.29 ± 33.92),(111.12 ± 34.50),and (42.85 ± 19.39) pg/ml,P＜ 0.05].Omentin were negatively correlated with homeostasis model assessment for insulin resistance(HOMA-IR) and body mass index(BMI).In the multiple stepwise regression analysis,only omentin was negatively correlated with BMI.Omentin may be involved in the development of PCOS by affecting obesity.