Urinary continence and pathological outcome after bladder neck preservation during radical prostatectomy: a systematic review and meta-analysis
10.3760/cma.j.issn.1000-6702.2016.03.004
- VernacularTitle:根治性前列腺切除术中保留膀胱颈对术后控尿功能恢复影响的Meta分析
- Author:
Xinjian LIU
;
Jianguo WEN
;
Qingwei WANG
;
Yan WANG
;
Youdong WAN
;
Kunkun YANG
;
Rongqun ZHAI
- Publication Type:Journal Article
- Keywords:
Prostatectomy;
Urinary incontinence;
Bladder neck;
Prostatic neoplasms
- From:
Chinese Journal of Urology
2016;37(3):174-178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct a systematic review to evaluate efficacy and safety of bladder neck preservation techniques during radical prostatectomy.Methods We searched PubMed,Embase,Medline,Central (the Cochrane Library,Issue 1,2013),CNKI,CBM from the inception to July 2015 for randomized or observational studies assessing the influence of preservation of bladder neck on the continence recovery and cancer control outcomes after radical prostatectomy.Two researchers evaluated the quality of included studies.A meta-analysis was conducted using Review Manager 5.0 software.Results Twelve observational and two randomized studies were analyzed.BNP group had a faster recovery of early continence than non-BNP group at 1 month[OR =2.88,95％ CI 1.80-4.60,P ＜ 0.05],3-4 months [OR =2.32,95％ CI 1.42-3.80,P ＜ 0.05].However there was no statistically significant difference in terms of continence rate at 6 months [OR =1.49,95％ CI 0.97-2.29,P =0.07] and 12 months [OR =0.99,95％ CI 0.70-1.39,P =0.93] among two groups.There was no significant difference in terms of PSM rate [OR =0.92,95 ％ CI 0.71-1.19,P =0.52] between BNP and non-BNP groups.Conclusions We found that preservation of the bladder neck result in earlier return of urinary continence without adversely affecting cancer control.
