Assessment of risk factors for prostatic tumor invasion in patients undergoing radical cystectomy
10.3760/cma.j.issn.1000-6702.2016.03.003
- VernacularTitle:根治性膀胱切除术患者前列腺受肿瘤累及的危险因素分析
- Author:
Mengqiang LI
;
Shaoqin JIANG
;
Weizhong CAI
;
Wei JIANG
;
Song ZHENG
;
Yongsheng LI
;
Enci XU
- Publication Type:Journal Article
- Keywords:
Bladder neoplasms;
Prostate adenocarcinoma;
Radical cystectomy;
Prostate-sparing cystectomy
- From:
Chinese Journal of Urology
2016;37(3):169-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the risk factors for prostate-sparing cystectomy by evaluating the risk of prostatic invasion or incidental prostatic adenocarcinoma (PCa) in bladder cancer (BCa) patients undergoing radical cystectomy.Methods The patients undergoing radical cystectomy from 2009 to 2014 in Fujian Medical University Union Hospital were enrolled to analyze the risk factors of prostatic tumor invasion.These factors included age,tumor size,location,quantity,histologic grade and pathologic stage.Results In the 123 male patients,the mean age was 60 years (range,31-78 years);23 (18.7％) patients had BCa or PCa in the prostate;14 (11.4％) had prostatic Bca;11 (8.9％) had PCa.The risk factors of prostatic BCa included multifocal bladder tumors (OR =26.70,P =0.032),tumor in the bladder neck and trigone(OR =17.13,P =0.013),pathological stage (OR =26.70,P ＜ 0.001).Among the 11 patients with PCa,3(27.3％) patients had Gleason score of ≥7,8(72.7％) patients ≤6 and 2(18.2％) patients had extracapsular extension.Three patients had clinically significant PCa.The factor of advanced age was associated with incidental PCa (P =0.003).Conclusion The risk factors of prostatic tumor invasion in patients undergoing radical cystectomy included advanced age,bladder tumor in bladder neck and trigone,muhifocal bladder tumors,and advanced pathological stage.
