Extremely elevated serum CA-125 concentration in patient with unruptured endometrioma A Case Report and Review of the Literature.
- Author:
Hee Suk OH
1
;
Soo Yong CHOUGH
;
Yong Kyun PARK
;
Ho Suk SAW
;
Chul Hwan KIM
;
Jun Young HUR
Author Information
1. Department of Obstetrics and Gynecology, Guro Hospital, College of medicine, Korea University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
CA-125;
Endometriosis
- MeSH:
Diagnosis;
Endometriosis*;
Female;
Humans;
Ovarian Neoplasms;
Rupture
- From:Korean Journal of Obstetrics and Gynecology
2002;45(2):318-322
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
CA-125 is an antigenic determinant expressed by more than 80% epithelial ovarian cancer. Although developed for use in the diagnosis and monitoring of epithelial ovarian cancer, elevations of CA-125 concentrations can also be associated with some normal physiologic conditions, various other malignancies and benign conditions. Adnexal cysts are frequently encountered during the reproductive years. 10 to 35% of benign cystic adnexal masses may be an endometrioma. Because endometriomas are not likely to resolve spontaneously, and may enlarge or rupture during period of observation, a test to detect an endometrioma would assist in the evaluation and management of adnexal cysts. Serum CA-125 concentration is seldom >100 U/ml in endometriosis. We reported a patient with endometrioma presenting with a very high CA-125 concentration, which may confuse diagnosis with ovarian cancer.
