Application of irreversible electroporation in the management of locally advanced pancreatic adenocarcinoma
10.3760/cma.j.issn.1007-8118.2016.01.022
- VernacularTitle:不可逆性电穿孔在局部进展期胰腺癌治疗中的应用
- Author:
Li YAN
;
Yongliang CHEN
- Publication Type:Journal Article
- Keywords:
Irreversible electroporation;
Locally advanced pancreatic adenocarcinoma;
Ablation
- From:
Chinese Journal of Hepatobiliary Surgery
2016;22(1):68-70
- CountryChina
- Language:Chinese
-
Abstract:
Irreversible electroporation (IRE) is a nontemperature based novel ablation therapy in which short highvoltage pulses are applied to treat tissues to permeabilize the cell membrane irreversibly and thus lead to cell apoptosis.Because it is characterized as non-thermal,IRE can reduce the risk of thermal damage to vital organs and structures so that it is more feasible for the treatment of unresectable pancreatic cancer and thus provide an ideal alternative to other thermal treatment modalities.This review aims to analyze current literature of IRE and to discuss the new progress of the application of IRE in the management of locally advanced pancreatic adenocarcinoma.
