Prevalence of Autoantibodies in Patients with Endometriosis.
- Author:
Seung Yup KU
1
;
Young Min CHOI
;
Byoung Joon JUNG
;
Chang Suk SUH
;
Seok Hyun KIM
;
Jung Gu KIM
;
Shin Yong MOON
;
Jin Yong LEE
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Autoantibody;
Prevalence;
Endometriosis;
Stage
- MeSH:
Antibodies;
Antibodies, Antinuclear;
Autoantibodies*;
Endometriosis*;
Female;
Humans;
Laparoscopy;
Laparotomy;
Lupus Coagulation Inhibitor;
Prevalence*;
Rheumatoid Factor
- From:Korean Journal of Obstetrics and Gynecology
2001;44(5):861-866
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: To assess the prevalence of autoantibodies in patients with endometriosis MATERIALS AND METHODS: The prevalence of autoantibodies were investigated in 93 patients with endometriosis diagnosed by laparoscopy or laparotomy. Autoantibodies, such as antithyroglobulin antibody, antimicrosomal antibody, antinuclear antibody (ANA), antiphospho -lipid antibody (APA), lupus anticoagulant (LAC), anti-dsDNA, and rheumatoid factor, were measured in sera of the subjects. The prevalence and distribution of autoantibodies were analyzed according to the stage of endometriosis. RESULTS: All seven autoantibodies were checked in 73 patients out of 93 patients. Autoantibodies were identified in 23 of 73 patients with endometriosis (31.5%). Antibodies detected were antithyroglobulin antibody (15.2%), ANA (12.0%), antimicrosomal antibody (8.7%), anti-dsDNA (5.4%), and rheumatoid factor (4.4%), APA (2.2%) and LAC (1.3%). The prevalence of autoantibodies did not differ by the AFS stage. CONCLUSION: Autoantibodies were detected in about one-third of patients with endometriosis. The prevalence of autoantibodies did not differ by the stage.
