MRI appearance of reversible splenial lesion syndrome in children
10.3760/cma.j.issn.1005-1201.2015.12.010
- VernacularTitle:儿童可逆性胼胝体压部病变综合征的MRI表现
- Author:
Jing ZHANG
;
Tao LI
;
Guangheng YIN
;
Tong YU
;
Yang LEI
;
Xintong SHI
;
Xiaomin DUAN
- Publication Type:Journal Article
- Keywords:
Reversible splenial lesion syndrome;
Magnetic resonance imaging;
Child
- From:
Chinese Journal of Radiology
2015;49(12):927-930
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnostic value of MRI in reversible splenial lesion syndrome (RESLES) in children.Methods The clinical and MRI imaging data of 14 cases of RESLES in children were retrospectively reviewed.There were 4 males and 10 females,aging 11 to 35 months.Average age was (20±3) months.MRI studies were conducted in all the cases.Two experienced doctors analyzed independently the images and reached consensus.Results Fourteen cases showed the single abnormal signal in the splenial of corpus callosum on the initial cerebral MRI.Lesions in 10 of 14 cases appeared as isointensity on T1WI,hypo-intensity in 4 cases.Lesions in 14 cases were appeared as hyper-intensity on T2WI,hyper-/slightly hyper-intensity on FLAIR T2WI.The lesions were round,oval or irregular,with fuzzy boundary.DWI showed round or oval high signal with clear boundary.No edema around the lesion and no occupying effect were detected.After treatment,8 of 14 cases were reviewed after 7-14 d,and the abnormal signal in the corpus callosum disappeared in 5 cases,while the range was significantly reduced in 3 cases.MRI were reexamined after 1-2 months in 5 cases,and the lesions disappeared in the corpus callosum.One case didn't have MRI examination again after treatment and the clinical symptoms disappeared.Conclusions The clinical manifestations of RESLES in children are lack of specificity.And the cerebral MRI imaging is characterized by the reversible solitary lesion of the splenium,which can provide a reliable basis for clinical diagnosis and prognosis.
