Research progress of podocyte antigen for idiopathic membranous nephropathy
10.3760/cma.j.issn.1008-1372.2016.03.046
- VernacularTitle:特发性膜性肾病足细胞抗原的研究进展
- Author:
Li LEI
- Publication Type:Journal Article
- Keywords:
Glomerulonephritis,membranous;
Podocytes;
Antigens;
Review
- From:
Journal of Chinese Physician
2016;18(3):473-476
- CountryChina
- Language:Chinese
-
Abstract:
Membranous nephropathy (MN) is a major cause of nephrotic syndrome in adults,and the inappropriate treatment may progress to end-stage renal disease.We know that membranous nephropathy can be divided into idiopathic membranous nephropathy (IMN) and secondary membranous nephropathy (SMN).The etiology of approximately 75％ of MN cases is idiopathic.In clinical work,we should distinguish IMN from SMN,which is the important premise for the diagnosis and treatment of MN.The definite pathogenesis of IMN remains unknown.However,some researchers have focused on the formation of immune complexes in the pathogenesis of MN in recent years.
