Circulating tumor cells for precision medicine in cancer

VernacularTitle:循环血肿瘤细胞为肿瘤精准治疗带来的机遇与挑战
Author: Siqi XIE
Publication Type:Journal Article
Keywords: Neoplasm circulating cells; Neoplasms/TH; Review
From: Journal of Chinese Physician 2016;18(3):468-470
CountryChina
Language:Chinese
Abstract: Over the last two decades,we have seen many advances in the biological underpinnings of many kinds of cancers that have had a significant impact either directly or indirectly on the management and ultimately on the prognostic outcome of this disease.Next-generation sequencing studies have provided further evidence to support the notion4 that cancer is a disease characterized by Darwinian evolution.However,Ones often fail to obtain the information in different stages of the tumor before making treatment decision.This may be the major reason for treatment failures.Currently,circulating tumor cells (CTCs) is considered as aliquid biopsy.By detecting CTCs at different stages of tumor and obtaining the biological characteristics of CTCs,ones can get information about tumor evolution at different stages.It might provide effective basis for individual therapy to tumors,and promote the accuracy of tumor treatment.