Clinical value of combined detection of serum CD4 + T cells and CD8 + T cells for advanced gastric cancer
10.3760/cma.j.issn.1008-1372.2016.01.017
- VernacularTitle:进展期胃癌血清CD4+T细胞、CD8+T细胞亚群检测的临床价值
- Author:
Min SONG
;
Huaiwu JIANG
;
Zonglin LI
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms/IM;
CD4-positive T-lymphocytes/IM;
CD8-positive T-lymphocytes/IM
- From:
Journal of Chinese Physician
2016;18(1):60-62
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of combined detection of serum CD4 + T cells and CD8 + T cells for advanced gastric cancer (AGC).Methods Serum levels of CI4 + T cells and CD8 + T cells were measured by flow cytometry and compared in 20 patients with AGC (experimental group) and 20 healthy adults (control group).Also,serum levels of CD4 + T cells and CD8 + T cells were measured by flow cytometry and compared before and after surgical treatment in the patients of experimental group.Results The serum levels of CD4 + T cells were decreased and CD8 + T cells were increased in patients with AGC.However,the serum levels of CD4 +T cells were increased and CD8 +T cells were decreased after surgical treatment (P ＜ 0.05).Conclusions The serum levels of CD4 + T cells and CD8 + T cell help to assess the immune status of patients with AGC,which contributes to the illness monitoring for AGC.
