Behavioral and neurophysiological abnormalities during cued continuous performance test in patients with mild traumatic brain injury
10.3760/cma.j.issn.1674-6554.2015.12.007
- VernacularTitle:轻度颅脑外伤患者提示性持续操作任务行为学及事件相关电位研究
- Author:
Ruhong WU
;
Yuechi LI
;
Bo DONG
;
Yumin MAO
;
Suhong WANG
;
Hongtao QU
;
Suinuan WANG
- Publication Type:Journal Article
- Keywords:
Mild traumatic brain injury;
Sustained attention;
Conflict monitoring;
Response inhibition
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2015;24(12):1083-1086
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the features and neural mechanisms of sustained attention and executive function in patients with acute mild traumatic brain injury (mTBI) by comparing and analyzing behavioral and event-related potentials of patients and healthy controls.Methods Seventeen patients with acute mTBI and seventeen healthy controls participated in a cued continuous performance test.Behavioral data and event-related potentials were collected and analyzed.Results 1.There were significant differences between the mTBI group and the control group in hitting number ((66.76±3.27), (69.12± 1.41)) ,reaction time((533.66±144.20) ms, (413.03±94.57) ms) and the number of errors of omission ((3.24±3.27), (0.88± 1.41)) (P＜0.05), but no significant differences in the number of false errors ((0.35±1.00), (0.53±0.87)) (P＞0.05).2.The amplitude of Go-N2 and Nogo-N2 were significantly smaller in mTBI group than that in control group (P＜0.05).The main effect of group was significant of N2 amplitude (P＜0.05), but main effect of condition and the interaction effect were not significant(P＞0.05).Group and condition had no significant main effect and interaction effect on the latency of N2 (P＞0.05).The amplitude of Go-P3 was significantly smaller in mTBI group than that in control group (P＜0.05),while not on the amplitude of Nogo-P3(P＞0.05).The main effect of group and condition were significant on P3 amplitude (P＜0.05),but the interaction effect was not significant(P＞0.05).Group and condition had no significant main effect and interaction effect on the amplitude of P3 (P＞0.05).Conclusion Patients with mTBI show impairments in sustained attention and conflict monitoring, but not in response inhibition.
