Progress in roles of cytokines in bone formation and remodeling
10.7644/j.issn.1674-9960.2016.02.018
- VernacularTitle:骨相关细胞因子在骨生长和重塑中的作用研究进展
- Author:
Fengkun JI
;
Haoyu LI
;
Ruiyun PENG
- Publication Type:Journal Article
- Keywords:
cytokines;
bone formation;
bone remodeling;
bone diseases;
developmental;
osteoarthritis;
hip;
bone mor-phogenetic protein;
transforming growth factor beta;
fibroblast growth factors
- From:
Military Medical Sciences
2016;40(2):150-153
- CountryChina
- Language:Chinese
-
Abstract:
Bone growth factors play an important role in the process of bone metabolism and perform a variety of physio -logical functions such as regulating bone growth , differentiation and remodeling .Meanwhile , these cytokines are associated with orthopedic disorder and therapy .The curative effect of the overturned sartorius iliac flap in repair of acetabular defect in developmental dysplasia of the hip proves to be good , but mechanism between the overturned flap and the surrounding bone tissue is unclear .This review briefly summarizes the functions and applications of several major cytokines in bone for -mation and remodeling , which may provide new ideas and methods for illuminating the mechanism of these cytokines during the repair of the acetabular defect .
