Effect ofBazheng powder combined with levofloxacin on renal tissue injure of patients with renal extracorporeal shockwave lithotripsy
10.3760/cma.j.issn.1673-4246.2016.03.007
- VernacularTitle:八正散加味结合甲磺酸左氧氟沙星对肾结石体外冲击波碎石术后肾组织损伤的影响
- Author:
Congkun XIANG
- Publication Type:Journal Article
- Keywords:
Kidney calculi;
Lithotripsy;
Shock waves;
Kidney injury;
Ba Zheng San;
Integrated Chinese traditional and Western medicine therapy
- From:
International Journal of Traditional Chinese Medicine
2016;38(3):216-219
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect ofBazheng powder combined with levofloxacin on renal tissue injure of patients after renal extracorporeal shockwave lithotripsy.Methods A total of 100 patients with renal calculus were randomly divided into a Bazheng powder group (50 patients) and a control group (50 patients). ESWL was used in the 2 groups. After ESWL operation, patients in the control group were administered with large amount of drinking water and appropriate exercises to promote stone removal. And on this basis, ethanesulfonic acid levofloxacin was administered for successive 3 days. TheBazheng powder group was additionally addedBazheng powder on the basis of the control group for 15 days. 15 days later, C Cys and NGAL and therapeutic effect in both groups were evaluated.Results The total effective rate of theBazheng powder group was significantly better than the control group (96%vs. 60%,χ2=16.842,P<0.01). The serum Cys C (0.97 ± 0.10 mg/Lvs. 1.13 ± 0.25 mg/L,t=4.202) and NGAL(4.04 ± 1.32 g/Lvs. 6.91 ± 2.96 g/L,t=6.262) in the Bazheng powder group decreased, the serum Cys C (0.95 ± 0.12 mg/Lvs. 1.09 ± 0.20 mg/L,t=4.244) and NGAL(4.66 ±1.57 g/Lvs. 7.19 ± 1.81 g/L,t=7.762) levels in the control group were also decreased after the treatment (P<0.01), andBazheng powde group of postoperative urinary NGAL level was significantly lower than the control group (t=2.137,P=0.035).ConclusionBazheng powder combined with ESWL can accelerate renal calculi removal and repair renal injury after ESWL operation. We also speculate that the best interval is 2 weeks for two lithoclasty operation.
