The infections and resistance of Haemophilus influenzae
10.3760/cma.j.issn.2095-428X.2016.04.005
- VernacularTitle:流感嗜血杆菌感染与耐药
- Author:
Aihua WANG
- Publication Type:Journal Article
- Keywords:
Haemophilus influenzae;
Antibiotic resistance;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;(4):256-258
- CountryChina
- Language:Chinese
-
Abstract:
Haemophilus influenzae (Hi)is an important human pathogen that causes severe infections inclu-ding meningitis,bacteremic pneumonia and sepsis,mostly affecting young children.The resistance of Hi to antimicro-bials has risen and wide variations exist in antibiotic resistance,both geographically and over time.The main mecha-nisms of resistance of Hi are those to β-lactam antibiotics.Antibiotic utilization is the main risk factors for the deve-lopment of antimicrobial resistance.Third -generation cephalosporins is the most effective antibiotic agent to treat the infections of Hi in children population.With continued research,progress toward a broadly effective vaccine to prevent infections caused by Hi is expected in the near future.
