The tidal breathing lung function changes and clinical significance of severe pneumonia in infants and young children during convalescent period
10.3760/cma.j.issn.2095-428X.2016.04.015
- VernacularTitle:重症肺炎恢复期婴幼儿潮气呼吸肺功能改变的意义
- Author:
Junying QIAO
;
Limin ZHANG
;
Bin LUAN
- Publication Type:Journal Article
- Keywords:
Severe pneumonia;
Infants and young children;
Lung function
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;(4):292-295
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes in tidal breathing lung function of severe pneumonia in re-covery phase and correlation with the condition and prognosis in infants and the young children.Methods Tidal breathing lung function of 44 cases of severe pneumonia infants and 50 cases of mild pneumonia infants in their recovery phase were measured by infantile spirometer made in Germany.According to ratio of exhaled volume at peak tidal expi-ratory flow to total expiratory volume(VPTEF /VE),severe pneumonia infants were divided into normal,mild,moderate and severe groups.All these children were followed up for the frequency of rehospitalization because of lower respiratory tract infections and the frequency of wheezing within 1 year after discharge.Statistical were analyzed by using t test andχ2 test.Results Compared with the mild pneumonia infants,the respiratory rate(RR)of the severe pneumonia infants was significantly increased [(36.31 ±0.78)times/min vs (30.83 ±0.74)times/min](P <0.01 );inspiratory time to expiratory time ratio(TI /TE)(0.65 ±0.01 vs 0.71 ±0.01 ),exhaled time at peak tidal expiratory flow(TPTEF) [(0.24 ±0.08)s vs (0.31 ±0.04)s]were significantly decreased (all P <0.01 );ratio of TPTEF to expiratory time (TPTEF /TE)[(1 9.1 5 ±0.77)% vs (23.00 ±0.51 )%],VPTEF /VE[(21 .28 ±0.86)vs (25.42 ±0.56)%]were significantly decreased (all P <0.01 ).The frequency of rehospitalization because of lower respiratory tract infections (χ2 =30.50,P <0.01 )and the frequency of wheezing within 1 year after discharge(χ2 =23.43,P <0.01 )in the severe pneumonia group were significantly higher than those of the mild pneumonia group;in the groups with different lung function damage by severe pneumonia,the frequency of rehospitalization because of lower respiratory tract infections (χ2 =1 0.64,P =0.033;χ2 =20.81 ,P =0.001 )and the frequency of wheezing (χ2 =1 0.53,P =0.037;χ2 =21 .25, P =0.001 )within 1 year after discharge in mild and severe group were significantly higher than those of the mild group,while there was no significant difference between normal group and mild group (P >0.05).Thirteen cases of se-vere pneumonia infants were followed up for 1 year.Of all these 1 3 cases,pulmonary function in 1 case restored to nor-mal within 3 months;that of 6 cases restored to normal within 6 months;the conditions of 3 cases restored to normal within 1 year;while the pulmonary function of other 3 cases was still abnormal 1 year after discharge.Conclusions Lung function damage of severe pneumonia infants is more serious than the mild pneumonia in infants in their recovery phase.For severe pneumonia infants,the more serious of lung function damages,the more likely to be re -hospitaliza-tion because of lower respiratory tract infections and wheezing in short time.
