The effect of brain metastases from NSCLC and treatment targeted plus radiotherapy on EGFR mutations
10.3760/cma.j.issn.1004-4221.2016.03.023
- VernacularTitle:EGFR 突变状态对 NSCLC 脑转移和放疗及靶向治疗疗效影响
- Author:
Jianzhong CAO
;
Hongwei LI
- Publication Type:Journal Article
- Keywords:
Epidermal growth factor receptor;
Brain metastases;
Lung
- From:
Chinese Journal of Radiation Oncology
2016;(3):296-300
- CountryChina
- Language:Chinese
-
Abstract:
Brain metastases (BM) are one of the main cause of death in patients with non small cell lung cancer ( NSCLC ).The prognosis is still poor, despite standard therapy based on surgery and radiotherapy.In recent years,with the deepening understanding of molecular mechanisms in lung cancer, epidermal growth factor receptor (EGFR) mutation might be considered as an effective therapeutic target for NSCLC with BM.Therefore,we review the current knowledge about the correlation between EGFR mutation with prevalence and prognosis in BM.
