Effect of exercise combined with calcium carbonate vitamin D on bone markers in early postmenopausal women
10.3969/j.issn.1673-4130.2016.04.008
- VernacularTitle:运动联合碳酸钙维生素D对绝经早期女性骨标志物的影响
- Author:
Zhuohua LI
;
Xueshi WU
;
Mintao CUI
- Publication Type:Journal Article
- Keywords:
bone turnover markers;
vitamin D;
bone mineral density;
postmenopausal osteoporosis;
clinical observation
- From:
International Journal of Laboratory Medicine
2016;37(4):452-454
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss efficacy of movement combined with calcium vitamin D in preventing osteoporosis in early postmenopausal women .Methods There were 100 cases ,which were divided into treatment group(50 cases) and control group(50 cases) ,to detect x-ray bone density and three kinds of absorptiometry bone markers as a baseline .The treatment group were given calcium carbonate ,vitamin D3 tablets ,continuous 3 ,6 ,12 ,18 months after the detection of bone mineral density and bone markers a-gain ,observe the change of various index .Results Early menopause women are very high in bone metabolic conversion rate .Com-bined therapy with calcium carbonate and vitamin D ,could significantly affect the level of the three types of bone markers ,there were negative phase ,and the changes in bone turnover markers were preference to BMD Treatment group three kinds of bone mark-ers had changed within three months ,fell by 25% ,12% and 10% respectively .Vitamin D and calcium carbonate effects on bone markers in monitoring ,and so ,three kinds of bone markers with different characteristics .Type Ⅰ collage carboxy-terminal peptide (β-CTX) in the early days could be a significant reduction in 3 months ,6 months after basic hadn′t changed much ;Type Ⅰ procol-lagen amino-terminal peptide (P1NP) and N-terminal osteocalcin (N-MID) reaction time was longer ,the heavy absorption resist-ance was remarkable changes after 6 months ,1 years maintained at a certain level ,and the change of bone mineral density(BMD) at least need more than 12 months .Conclusion Exercise and calcium carbonate and vitamin D supplement ,which could effectively re-duce the bone absorption and improve vitamin D levels ,prevent bone loose women in early menopause has great significance
