Advance in the treatment of children with hepatoblastoma
10.3760/cma.j.issn.2095-428X.2016.03.003
- VernacularTitle:儿童肝母细胞瘤治疗进展
- Author:
Xiaojun YUAN
- Publication Type:Journal Article
- Keywords:
Child;
Hepatoblastoma;
Treatment;
Multidisciplinary
- From:
Chinese Journal of Applied Clinical Pediatrics
2016;(3):171-175
- CountryChina
- Language:Chinese
-
Abstract:
Hepatoblastoma (HB)is the most common malignant liver tumor in children.Surgical resection was the major treatment approach to HB,whereas more than 60% patients had unresectable mass at diagnosis,even though complete resection,there were about 30% patients recurrent.With the introduction of adjuvant chemotherapy,the treat-ment of HB has been developed to multidisciplinary cooperation from single surgical resection,such strategy greatly im-proved the prognosis of children with HB,but there still be a great challenge in the treatment of high -risk patients.All famous children′s HB study groups have begun to focus on the optimization of chemotherapy,surgery opportunity,strate-gy based on risk -stratification,looking for new potential therapeutic targets and prognosis -related risk factors.
