A review of monoclonal antibody therapy for cancer and prospects
10.3867/j.issn.1000-3002.2016.01.001
- VernacularTitle:肿瘤抗体治疗的历史回顾与展望
- Author:
Beifen SHEN
- Publication Type:Journal Article
- Keywords:
tumor;
antibody;
treatment
- From:
Chinese Journal of Pharmacology and Toxicology
2016;(1):1-6
- CountryChina
- Language:Chinese
-
Abstract:
As a targeted drug,monoclonal antibodies have been successful in tumor therapy. Thus,antibodies and related products are the fastest-developing biological agents. There are currently more than 40 monoclonal antibodies in the market that have been approved by the FDA,half of which are used to treat cancer. In recent years,a new generation of antibody drugs,such as human anti?body,glyco-engineered antibody,bispecific antibody,antibody-drug conjugates and immune check?point blockade antibody,have successfully cured various malignant tumors. In this paper,the history of antibody treatment for cancer,and the development and prospect of anti-tumor antibodies have been reviewed.
