Ultrasonic findings of heptobiliary involvement in Langerhans′ cell histiocytosis in children
10.3760/cma.j.issn.1004-4477.2016.01.009
- VernacularTitle:儿童朗格汉斯细胞组织细胞增生症肝胆侵犯的超声表现
- Author:
Jing SHI
;
Jun DU
;
Wei WU
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Histiocytosis,langerhans-cell;
Child;
Liver;
Biliary tract
- From:
Chinese Journal of Ultrasonography
2016;(1):40-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the sonography features of heptaobiliary involvement of pediatric Langerhans′cell histiocytosis ( LCH) . Methods Nine pediatric patients with LCH confirmed by the clinical presentation ,biochemical tests and pathologic results of our hospital were retrospectively analyzed . Results Eight patients were seen in multi‐system LCH ,while one patient only had liver involved . All patients showed varying hepatomegaly with multiple distributed lesions in ultrasound images . According the lesion distribution features ,they could be classified into three types:central type(6/9) ,peripheral type(1/9) and diffuse type(2/9) . In ultrasonography ,they manifested as linear lesions alongside the central portal veins , multi‐nodular and randomly distributed lesions in liver parenchyma ,or both of them . Eight bile‐duct involved patients behaved with unevenly thicked bile‐duct walls ,stenosis or dilated bile‐ducts ,and even sclerosing cholangitis , some of them with cholelithiasis . Conclusions Pediatric LCH patients with heptobiliary involved are seemed mainly in multi‐system LCH ,while it is rare but possible that pathological Langerhans′cell only infringe on liver and bile‐ducts . The ultrasound imaging findings of pediatric LCH liver infiltration are with characteristic and are helpful for the early diagnosis and clinical procedure .
