Research Review on Antifungal Drug Resistance Mechanisms in Candida Spp
10.3969/j.issn.1671-7414.2016.01.017
- VernacularTitle:念珠菌耐药机制研究进展
- Author:
Xin HOU
;
Li ZHANG
;
Yingchun XU
;
Yupei ZHAO
- Publication Type:Journal Article
- Keywords:
Candida spp;
antifungal drug resistance;
antimicrobial susceptibility test;
resistance gene
- From:
Journal of Modern Laboratory Medicine
2016;(1):60-64
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,the epidemiology of Candida infection has changed.Although Candida albicans is still the main pathogens causing invasive candidiasis,non-albicans Candida species are increasingly encountered.Different Candida species show distinct sensitivity of different drugs.The emergence of drug resistance has become the main problem of Candida in-fection treatment.Antifungal resistance of clinical Candida infections often lead to treatment failure.The review of resistance mechanisms and the effect on clinical treatment is very significant to improve the prognosis of patients and strengthen the control of infection.This text reviews the present state of the detection of mechanisms of resistance in Candida spp .
