Clinical Significance of Neutrophils/Lymphocyte and Platelet/Lymphocyte Ratio of Peripheral Blood in Patients with Myasthenia Gravis
10.3969/j.issn.1671-7414.2016.01.018
- VernacularTitle:重症肌无力患者外周血中性粒细胞／淋巴细胞比值和血小板／淋巴细胞比值的临床意义
- Author:
Tingting LIU
;
Hu LI
;
Wei MA
;
Yan CHEN
;
Mingli GU
;
Lei ZHANG
;
Anmei DENG
- Publication Type:Journal Article
- Keywords:
myasthenia gravis;
neutrophils/lymphocyte ratio;
platelet/lymphocyte ratio;
inflammation
- From:
Journal of Modern Laboratory Medicine
2016;(1):65-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of neutrophils/lymphocyte ratio (NLR)and platelet/lymphocyte ratio (PLR)of peripheral blood in patients with myasthenia gravis (MG).Methods 54 patients with MG treating from Jan-uary 2013 to December 2013 in Changhai hospital and 57 healthy adults who received check-up were enrolled the study as MG group and control group.WBC count,NLR and PLR were compared between two groups and among different clinical classifications in MG patients.The area under the receiver operating characteristic (ROC)curve was performed to evaluate these indicators’diagnostic value for MG.Results The WBC count,NLR and PLR in MG group were (6.85±0.37)×109/L,2.48±0.19 and 118.79±6.38 respectively,which were significantly higher than (5.87±0.12)×109/L,1.59±0.06 and 102.01±3.45 in control group (P <0.05).The area under the ROC curve of WBC count,NLR and PLR were 0.559,0.717 and 0.581 respectively.PLR of MG patients with type Ⅲ or Ⅳ was significantly higher than that of patients with typeⅠ,Ⅱ(P <0.05).Conclusion NLR and PLR of MG patients increased significantly.The diagnostic value of NLR is higher,and PLR may be associated with the severity of disease.
