The multivariate analysis of CA125 and inflammation indicators in gynecological diseases
10.3969/j.issn.1673-4130.2016.02.012
- VernacularTitle:妇科疾病中CA125与炎症相关指标的多因素分析
- Author:
Changye LI
;
Min HUANG
;
Li WU
;
Wenting TANG
;
Zuoxin DENG
;
Qiaopei CHEN
- Publication Type:Journal Article
- Keywords:
CA-125 antigen;
inflammation;
genital diseases,female;
neutrophil-to-lymphocyte ratio
- From:
International Journal of Laboratory Medicine
2016;(2):171-173
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate whether there is a correlation between carbohydrate antigen125(CA125) and inflammation indicators in gynecological diseases ,analyze the possible mechanism of the disease .Methods Retrospectively analyze the regression and correlation between CA125 and routine blood classification indicators in 4 291 patients from department of reproductive health and gynaecology .Stepwise multiple regression model was used to analyze the common disease from department of gynaecology in‐cluding pelvic infection ,endometriosis ,uterine fibroids .Results The analysis of 4 291 cases showed that there was a correlation be‐tween CA125 and leukocyte count ,neutrophil‐to‐lymphocyte ratio (NLR) .The correlation coefficient was 0 .170 .For diseases of different types ,in patients with pelvic inflammation and endometrial ectopic there were correlations between CA125 and NLR .The correlation coefficient were 0 .290 and 0 .342 respectively .Conclusion There might be a correlation between CA125 and the inflam‐mation indicators .It should be carefully to diagnose cancer related diseases ,especially when inflammatory factors and CA125 in‐creased at the same time .
