The advantages and research progress of T cells of the chimeric antigen receptor in the treatment of primary tumors
10.11958/58917
- VernacularTitle:嵌合抗原受体T细胞治疗原发性肿瘤的优势与研究进展
- Author:
Wei ZHANG
;
Dandan YAN
;
Li GAO
;
Mingliang SHAO
;
Huimin YAN
- Publication Type:Journal Article
- Keywords:
Car T;
cell therapy;
neoplasms;
review
- From:
Tianjin Medical Journal
2016;44(2):253-256
- CountryChina
- Language:Chinese
-
Abstract:
Chimeric antigen receptor (Car) T cells, not only have the characteristics of strong specific recognition of tu-mor antigens, but also have destruction and high affinity advantages, thus receiving more attention. Although it has played a lot of advantages in anti-tumor, it still has some shortcomings, which needs to be further optimized to improve the safety of its clinical application. In this study, The cell structure and biological function, treatment process, application development and application risk of Car T cells are reviewed, which provide references for further clinical immunotherapy of Car T.
