Analysis of Volatile Constituents in Disposable Infusion Set and Nasal Cannula by Gas Chromatography-Mass Spectrometry
- VernacularTitle:一次性输液器和鼻氧管中挥发性物质的气相色谱-质谱法联用分析
- Author:
Junwei WU
;
Lin ZHONG
;
Bin WU
;
Xinjun XU
;
Rongwei YAN
- Publication Type:Journal Article
- Keywords:
Disposable infusion set;
Nasal cannula;
GC-MS
- From:
China Pharmacist
2016;19(3):498-501
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To characterize the volatile compounds in 10 batches of disposable infusion sets and 6 batches of nasal can-nulas by GC-MS and determine the main odor-active compounds. Methods:The volatile components were extracted using a headspace sampler. An HP-5MS capillary column (30 m × 0. 25 mm,0. 25 μm) was adopted, and the qualitative analysis was performed by total ion chromatography ( TIC) of full scan with temperature programmer. Results:A total of 19 major volatile compounds were identified, which were hydrocarbon, alcohol and carbonyl compounds (such as aldehyde and ester). Based on the combination of odor test and GC-MS, the concentration of alcohol compounds (2-ethyl hexanol, 2-EH) had the most notable effect on the odor of samples. Conclu-sion:The samples with unacceptable order contain 2-EH with relatively high content, which should be paid more attention.
