The application value of four detection methods in clinical diagnosis of tuberculosis
10.3969/j.issn.1673-4130.2016.05.002
- VernacularTitle:4种检测方法在结核病临床诊断中的应用价值
- Author:
Jialing WU
- Publication Type:Journal Article
- Keywords:
pulmonary tuberculosis;
T-cell-based spot test for tuberculosis infection;
tuberculosis antibody;
rapid culture test for Mycobacterium tuberculosis;
sputum or bronchoalveolar lavage fluid smear
- From:
International Journal of Laboratory Medicine
2016;37(5):580-582
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical diagnostic value of four kinds of diagnostic methods ,including pulmonary tubercu‐losis ,including T‐cell‐based spot test for tuberculosis infection(T‐SPOT .TB) ,rapid culture test for Mycobacterium tuberculosis , combined detection of IgM and IgG antibodies in tuberculosis and sputum or bronchoalveolar lavage fluid smear .Methods A total of 516 cases of patients who were initially diagnosed with tuberculosis and without medication were collected from October 2014 to May 2015 in this hospital .T‐SPOT .TB ,rapid culture test for Mycobacterium tuberculosis ,combined detection of IgM and IgG anti‐bodies in tuberculosis and sputum or bronchoalveolar lavage fluid smear were performed in all patients .The sensitivity of these methods were calculated and compared .Results The sensitivity of T‐SPOT .TB(88 .76% ) was higher than that of rapid culture test for Mycobacterium tuberculosis(45 .74% ) ,combined detection of IgM and IgG antibodies in tuberculosis(72 .87% ) and sputum or bronchoalveolar lavage fluid smear(17 .25% ) ,all had statistically significant differences(P< 0 .01) .Conclusion T‐SPOT .TB might have significant application value for detecting Mycobacterium tuberculosis infection and assisting the diagnosis of tuberculo‐sis .Meanwhile ,combining with other detection methods could greatly improve the diagnostic rate and meet different clinical needs .
