Efficacy of different duration of low-carbohydrate diet intervention on glycosylated hemoglobin in ;type 2 diabetes patients：a Meta analysis

VernacularTitle:不同时间的低碳水化合物饮食干预对2型糖尿病患者糖化血红蛋白影响的Meta分析
Author: Yanyun ZHANG ; Shanshan MA ; Lili WANG ; Chenglin ZHANG ; Xiaohua WANG
Publication Type:Journal Article
Keywords: Diabetes,type 2; HbA1c; Low-carbohydrate diet
From: Chinese Journal of Practical Nursing 2016;32(4):317-320
CountryChina
Language:Chinese
Abstract: Objective To evaluate the efficacy of different duration of low-carbohydrate diet (LCD) intervention on glycosylated hemoglobin (HbA1c) in type 2 diabetes mellitus (T2DM) patients. Methods Randomized controlled trials (RCTs) of LCD intervention in T2DM patients were collected in the databases such as MEDLINE, PubMed, OVID, China National Knowledge Infrastructure, China Scientific Journal Database by VIP, Wanfang database, et al.Data were analyzed by RevMan 5.3 version. Results Eight RCTs were included. The results of Meta-analysis indicated that the effects of lowering HbA1c by LCD intervention for three (Z=2.28, P<0.05) and six months (Z=14.99, P<0.01) were better than other diabetes diets, but there was no significant statistical difference between one (Z=0.65, P=0.51) and two years (Z=1.62, P=0.10). Conclusions Hypoglycemic effect of short-term LCD was better than other diabetes diets, but long-term effect was similar between them. LCD was a therapeutic diet suitable for T2DM patients.