Analysis of clinical manifestations and drug resistance in purulent meningitis caused by Escherichia coli in ;neonates
10.3969/j.issn.1000-3606.2016.03.003
- VernacularTitle:新生儿大肠埃希菌化脓性脑膜炎临床特点及耐药性分析
- Author:
Zengxian SUN
;
Juhong LAN
;
Yali ZHANG
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
purulent meningitis;
extended spectrumβ-lactamases;
neonate
- From:
Journal of Clinical Pediatrics
2016;34(3):172-175
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and drug resistance of neonatal purulent meningitis caused by Escherichia coli. Methods The clinical data of 46 neonates diagnosed with purulent meningitis caused by Escherichia coli were retrospectively analyzed from June 2004 to June 2014. The neonates were divided into community acquired infection group and nosocomial infection group, or early group (from June 2004 to May 2009) and late group (from 2009 June to June 2014). Result Fever, hypothermia, lethargy, poor feeding, tachypnea, and tachycardia were common clinical manifestations in all neonates. The detection rate of ESBLs was signiifcantly higher in nosocomial infection group than that in community acquired infection group (P?
