Analysis of the clinical effect of methylprednisolone in the treatment of patients with acute myelitis
10.3760/cma.j.issn.1008-6706.2016.03.021
- VernacularTitle:甲泼尼龙冲击治疗急性脊髓炎的临床疗效分析
- Author:
Linghong WANG
;
Juxiu HUANG
;
Yuping LI
;
Litong JIN
- Publication Type:Journal Article
- Keywords:
Myelitis;
Methylprednisolone;
Dexamethasone
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(3):397-399
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical curative effect and complication of methylprednisolone in the treatment of patients with acute myelitis.Methods 42 patients with acute myelitis were selected and randomly divid-ed into two groups,21 cases in each group.The control group was treated with dexamethasone,the observation group was treated with methylprednisolone.After treatment,the clinical parameters and effect of the two groups were com-pared.Results The total effective rate of the observation group was 85.7%,which was higher than 42.9% of the control group (χ2 =2.41,P <0.05).The improvement of muscle strength,restore micturition,walk on their own time in the observation group were (10.1 ±4.1)d,(7.1 ±3.4)d,(16.1 ±4.2)d,respectively,which were better than (23.4 ±7.3)d,(10.2 ±3.1)d,(22.6 ±7.3)d in the control group(t =3.15,1.69,1.97,all P <0.05).The total incidence of gastrointestinal reaction and complication rates of the observation group was 4.8%,which was lower than 19.0% of the control group (χ2 =6.37,P <0.05).Conclusion In treatment of patients with acute myelitis,methyl-prednisolone has good effect,which should be used in clinical practice.