Clinical Study on Oral Administration and External Application of Yanyuxiao on Acute Traumatic Synovitis of Knee Joint
10.3969/j.issn.1005-5304.2016.03.006
- VernacularTitle:炎愈消内服外敷治疗膝关节急性创伤性滑膜炎临床研究
- Author:
Guisheng LU
;
Jie CHEN
;
Xiaopeng GAO
;
Hongbin LI
- Publication Type:Journal Article
- Keywords:
traumatic synovitis of knee joint;
TCM therapy;
Yanyuxiao
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(3):20-22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of oral administration and external application of Yanyuxiao on acute traumatic synovitis of knee joint. Methods Totally 86 patients with acute traumatic synovitis of knee joint were randomly divided into treatment group and control group, with 43 cases in each group. The patients in the two groups were treated with conventional western medicine. Patients in the control group orally took diclofenac sodium at the same time, while patients in the treatment group received oral administration and external application of Yanyuxiao Formula for 2 weeks. The scores of pain, swelling and function of knee joint and the levels interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) of joint fluid before and after the treatment were observed. The efficacy and the recurrence rate in three months after treatment were compared. Results The scores of pain, swelling and function of knee joint of the two groups significantly decreased after treatment, and the scores of pain, swelling and function of knee joint of the treatment group in one and two weeks were lower than those of the control group (P<0.05, P<0.01). The levels of synovial fluid IL-6 and TNF-α of the treatment group were lower than those of the control group after two-week treatment (P<0.01); the total effective rate was higher than that of the control group (P<0.05). The recurrence rate of the treatment group was lower than that of the control group after discharged for 3 months (P<0.05). There were no obvious adverse reactions during the treatment period. Conclusion Oral administration and external application of Yanyuxiao Formula has definite efficacy for acute traumatic synovitis of knee joint, with good safety.
