Relation of white blood cell count and cardiac events changes in patients with acute ST-segment elevation myocardial infarction treated with reperfusion
10.3760/cma.j.jssn.1673-4904.2016.03.005
- VernacularTitle:急性ST段抬高型心肌梗死早期再灌注后白细胞与心脏事件的关系
- Author:
Shengqiang ZHANG
;
Xianghua CHEN
;
Yang ZHANG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Reperfusion;
Leukocyte count;
Cardiac events
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(3):206-209
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between white blood cell(WBC) count and cardiac events in acute ST-elevation myocardial infarction(STEMI) patients treated with reperfusion in the early stage. Methods Two hundred and thirty-five patients with acute STEMI were divided into two groups:percutaneous coronary intervention group (PCI group, 97 patients) and thrombosis therapy group (138 patients). WBC count and cardiac events of the two groups before and after treatment (3 h and the second day and the third day) were recorded and compared. Results The level of WBC count had no changes in two groups before and after treatment in first 3 h (P>0.05) , while the level of WBC count was significantly decreased, and the level of WBC count was significantly lower in PCI group than that in thrombosis therapy group (P<0.05). The rate of no cardiac events and two cardiac events in two groups has no significant differences (P > 0.05). The rate of one cardiac events in PCI group was significantly higher than that in thrombosis therapy group (P<0.05). The rate of three cardiac events in PCI group was significantly lower than that in thrombosis therapy group (P<0.05). WBC count had a positive correlation with cardiac events rate (r = 0.231, P < 0.05). Conclusions Primary percutaneous coronary intervention decreases WBC count and cardiac events rate. In patients with acute myocardial infarction, level of WBC count has positive relationship with cardiac events.
