Study on Extracting Process ofSan Ao Decoction by Multi-indexes Grading Method
10.3969/j.issn.1005-5304.2016.04.024
- VernacularTitle:多指标综合评分法优选三拗汤提取工艺研究
- Author:
Jinhua ZHANG
;
Taoshi LIU
;
Jianming CHENG
;
Xiaolin BI
;
Haifeng QIAN
;
Dongdong CHEN
- Publication Type:Journal Article
- Keywords:
San Ao Decoction;
orthogonal test;
extracting process
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(4):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To simultaneously determinate the contents of four active ingredients (Ephedrine Hydrochloride, Pseudoephedrine Hydrochloride, Amygdalin and Glycyrrhizinate) ofSan Ao Decoction by HPLC; To optimize the extracting process ofSan Ao Decoction.Methods The orthogonal test was employed. Volume of water, time of extraction and times of extraction were set as investigation factors; the transport rates of Ephedrine Hydrochloride, Pseudoephedrine Hydrochloride, Amygdalin and Glycyrrhizinate and the extraction rates were set as investigation indexes to conduct multi-indexes grading.Results The influence factors of the extraction ofSao Ao Decoction were the times of extraction > decoction time > the volume of water. The best extraction condition was: ten fold water; extract for three times; 1 h for each time.Conclusion The optimized extraction process is stable and feasible.
