Study on Refining Water Extract ofBushen Yangxue Granules by Chitosan Flocculation
10.3969/j.issn.1005-5304.2016.04.026
- VernacularTitle:壳聚糖絮凝法精制补肾养血颗粒水提液的工艺研究
- Author:
Yanjiao DU
;
Chen KANG
;
Maobo DU
;
Shuo SHEN
;
Manling LI
;
Lina LIANG
;
Shuzhi LIU
- Publication Type:Journal Article
- Keywords:
Bushen Yangxue Granules;
icariin;
chitosan;
refining process;
orthogonal test
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2016;23(4):98-101
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize refinement of water extract from Bushen Yangxue Granules by chitosan flocculation.Methods According to the content of icariin detected by HPLC, the waters amount, extraction time and extraction times were evaluated by orthogonal design. The effects of the solution concentration, clarifying temperature and the amount of clarifying agent on the flocculation clarification processes were optimized with the content of icariin and polysaccharides.Results The optimum water extraction processes A2B1C3 were follows: 10 times amount of water, three times extraction and 1 h for each extraction process. The optimized flocculation clarification processes A1B2C3 were as follows: solution concentration was 0.4 g/mL, the clarifying temperature was 40℃ and the addition of chitosan was 0.1%.Conclusion The optimized refining process is stable and feasible.
