Relationship between HBV genotype and liver damage in northern China
10.3969/j.issn.1673-4130.2016.06.018
- VernacularTitle:中国北方地区 HBV 主要基因型和肝损伤相关性研究
- Author:
Shujun GUO
;
Juan LI
;
Pei QU
;
Miaomiao ZHAO
;
Shujing SONG
- Publication Type:Journal Article
- Keywords:
genotype;
HBV DNA;
liver fibrosis;
liver function;
hepatitis B virus e antigen
- From:
International Journal of Laboratory Medicine
2016;37(6):763-764
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship between hepatitis B virus (HBV) genotype and HBV DNA ,liver fibrosis ,liver function and HBeAg .Methods HBV genotypes ,HBV DNA ,liver fibrosis indicators and alanine aminotransferase(ALT ) ,aspartate aminotransferase(AST ) ,total bilirubin(TBIL) ,albumin(ALB) and HBV e antigen(HBeAg) were detected in patients with serum hepatitis .All data were statistically analyzed .Results There was no significant difference of HBV DNA ,ALT ,AST ,TBIL ,ALB , procollagen- Ⅲ -peptide ,type Ⅳ collagen ,hyaluronic acid and laminin between patients with B and C genotype infection (P> 0 .05) . However ,HBeAg level in patients with C genotype infection was higher than that in patients with B genotype infection (P< 0 .05) . Conclusion There might be no significant difference of HBV DNA ,liver function and liver fibrosis between patients with B and C genotype infection ,but HBeAg level in patients with C genotype infection could be higher than patients with B genotype infection .
