Evaluation microscopic observation drug susceptibility assay in detecting mycobacterium tuberculosis in sputum
10.3969/j.issn.1673-4130.2016.06.004
- VernacularTitle:显微镜观察药物敏感性技术快速检测痰标本中结核分枝杆菌的研究
- Author:
Youhui FU
;
Shu ZHANG
;
Haitao WANG
;
Feng CAI
;
Yanhong FAN
;
Zhongyi HU
- Publication Type:Journal Article
- Keywords:
sputum;
Mycobacterium tuberculosis;
microscopic observation drug susceptibility assay
- From:
International Journal of Laboratory Medicine
2016;37(6):728-730
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of microscopic observation drug susceptibility assay (MODS)for testing Mycobacteri-um tuberculosis in sputum ,and to evaluate its clinical value .Methods A total of 150 sputum samples were collected from patients with pulmonary tuberculosis ,and Mycobacterium tuberculosis were detected by Lowenstein-Jensen (L-J) method and MODS ,and compared the results of the two methods .Results The concordance rates of the test results of sputum sample between MODS and L-J was 77 .8% .The sensitivity and specificity of MODS were 93 .3% and 70 .0% ,positive predictive value (PPV ) was 60 .8% , negative predictive value (NPV) was 95 .4% ,as well as accuracy by MODS was 77 .8% .Conclusion MODS assay could be used as a rapid tuberculosis detection method ,with rapid ,sensitive ,simple ,and other advantages .
