Clinical value of PCT in guiding treatment of infection in elderly patients with heart failure
10.3969/j.issn.1673-4130.2016.06.011
- VernacularTitle:血清降钙素原监测在老年心力衰竭患者抗感染治疗中的应用研究
- Author:
Xiaoqing LI
;
Ying XU
;
Peng ZHOU
- Publication Type:Journal Article
- Keywords:
heart failure;
procalcitonin;
infection
- From:
International Journal of Laboratory Medicine
2016;37(6):746-748
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical value of procalcitonin (PCT ) in guiding treatment of infection in elderly patients with heart failure .Methods A total of 120 cases of elderly patients with heart failure and infection were divided into control group (50 cases) ,receiving conventional anti-infection treatment ,and observation group(70 cases) ,receiving adjusted anti-infection treat-ment based on serum PCT levels .Treatment efficiency ,cost of treatment ,hospitalization duration and other indicators were com -pared between the two groups .Results Effective rate of observation group was 78 .57% ,which was not significantly different with the 78 .00% of control group ( P > 0 .05) .Cost of treatment ,hospitalization duration ,application time of antibiotics ,antibacterial drug costs ,superinfection and mortality were significantly different between the two groups (P< 0 .05) .After treatment ,levels of e-rythrocyte sedimentation rate ,C-reaction protein ,white blood cells and neutrophil in the two groups were significantly improved (P< 0 .05) .After treatment ,C-reaction protein level of observation group was lower than control group (P < 0 .05) .Conclusion PCT based anti-infection treatment could help shorten the treatment time ,reducing treatment costs and improving outcomes ,and might be worthy of clinical application .
