Cells and cellular interactions in the pathogenesis of idiopathic pulmonary fibrosis
10.16571/j.cnki.1008-8199.2016.03.020
- VernacularTitle:特发性肺纤维化的细胞学研究进展
- Author:
Tingting XIA
;
Liting ZHANG
;
Fang CHEN
;
Kang SONG
- Publication Type:Journal Article
- Keywords:
Idiopathic pulmonary fibrosis;
Immune cells;
Fibroblast;
Fibrocyte;
Myofibroblast;
Endothelial cells;
Alveolar ep-ithelial cells
- From:
Journal of Medical Postgraduates
2016;29(3):314-318
- CountryChina
- Language:Chinese
-
Abstract:
Idiopathic pulmonary fibrosis ( IPF) is a kind of Interstitial lung disease with cause unknown,which is aggressive for its increasing prevalence and high morbidity and mortality.At present the pathogenesis of IPF is not entirely clear, but cells and cel-lular interactions play a decisive role on the alveolar inflammation and fibrosis results.We review IPF related cells of interest ( immune competent cells and fibroblast, fibrocyte, myofibroblast, endothelial and alveolar epithelial cells) , to summarize cells and cellular in-teractions in the pathogenesis of IPF,and discuss new research directions and therapeutic targets.
