Preliminary investigation and analysis of irregular antibodies of blood group before patients′transfusion
10.16571/j.cnki.1008-8199.2016.03.010
- VernacularTitle:29770例输血前血型不规则抗体患者调查与分析
- Author:
Wen TANG
;
Peiyuan ZHU
;
Jingmei YAN
;
Dong YE
;
Fang YAN
;
Jianfeng LUAN
- Publication Type:Journal Article
- Keywords:
Irregular antibodies;
Blood transfusion safety;
Micro column gel method
- From:
Journal of Medical Postgraduates
2016;29(3):272-275
- CountryChina
- Language:Chinese
-
Abstract:
Objective Irregular antibody screening and identification are very important to reduce hemolytic reaction.The dis-tribution of irregular antibodies of blood group was analyzed in patients, to provide evidence for using Micro column gel test to detect and identify irregular antibodies transfusion safety. Methods Micro column gel anti-globulin technique was used to screen the irregular an-tibodies and cross-matching in 29770 patients.If the serum had irregular antibodies, the spectrum cells were used to identify the specific-ity of irregular antibodies. Results Among 29 770 patients, 120 cases had irregular antibodies of blood group.The positive rate was 0.4%.The irregular antibodies include Rh system(n=67),MNS system (n=7), Lewis system(n=5),cases of Kidd system(n=3) and undefined specified antibodies(n=38).Among the 120 antibody-positive patients, 70 were female patients and 50 were male patients. Further study showed that the pregnancy history was to the main factor causing irregular antibodies in women (46 positive cases among 70 female patients) . Conclusion The study showed that some patients had irregular antibodies of blood group, especially female patients with pregnancy history.These results suggested that irregular antibody screening and cross-matching by micro column gel method in pa-tients before transfusion had great significance for ensuring the blood transfusion safety.
